Connective Tissue Activation. I. The Nature, Specificity, Measurement and Distribution of Connective Tissue Activating Peptide
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چکیده
منابع مشابه
Connective tissue activation. XXVIII. A connective tissue activating peptide from human urine.
A protein factor in human urine which has the ability to activate connective tissue cells has been identified and partially purified; it appears to be different from epidermal growth factor and IgG. This urinary connective tissue activating factor (CTAP-U) is nondialyzable, labile to protease, stable to thiols, heat, and acid, and has an acidic isoelectric point. Purified preparations of CTAP-U...
متن کاملinductive effect of palatal connective tissue on alveolar mocosa after subepithelial connective tissue graft clinical & histologic study
چکیده ندارد.
15 صفحه اولConnective Tissue Activation
A polypeptide which induces hypermetabolism in normal synovial fibroblasts in tissue culture is described. The metabolic changes induced included a marked increase in hyaluronate formation, lactate formation and glucose uptake; formation of soluble and fibrous collagen was depressed. An assay method is presented which permits quantitative comparisons of samples for connective tissue activating ...
متن کامل1362 Connective Tissue Activation
14 C-gldcommine and '5S04-labeled glycosaminoglycan (GAG) synthesis, 2) responsiveness to autacdid mediators, and 3) perfarmance following maximal stimulation. Under basal conditions, SF synthesized and secreted 2-3 times more radioactive hyaluronic acid than the NF (P < 0.001); molecular volume by gel chromatography was similar and suggested a high molecular weight ptoduct. SF were essentially...
متن کاملConnective tissue activation. XVII. Radioimmunoassay of a human platelet derived connective tissue activating peptide (CTAP-III) and specificities of anti-CTAP-III sera.
The platelet-derived connective tissue activating peptide (CTAP-III) has been shown to be an important factor stimulating the metabolism and proliferation of human connective tissue cell strains, including synovial tissue cells. The quantities of CTAP-III affecting the cellular changes and the amounts of various biologic fluids and tissues are small. The objectives of this study were to develop...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1971
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780140107